求翻译：长期药物治疗无效者；因药物依赖影响生活质量或出现药物不良反应者；无法耐受终身服药者；规律服药但出现反流相关并发症者（食管炎，食管狭窄，Barrett，s 食管）及伴有HH者。是什么意思？

Long-term medical therapy; affect the quality of life due to drug dependence or adverse drug reactions; can not tolerate medication for life; regular medication, but there were reflux-related complications (esophagitis, esophageal stricture, Barrett, s esophagus) and with those who have HH.

Long-term treatment for drug-dependent persons; invalid affects the quality of life or adverse drug reaction; it is not possible to those who are resistant to life-long medication medication; laws governing anti-influenza-related complications but there are narrow (oesophagitis and oesophageal Barre

Long-term medicine treatment invalid; Because the medicine dependence influence quality of life or appears the medicine not good reactor; Is unable to endure the lifelong people treated with medication; But the rule takes medicine appears the regurgitation related complication (esophagitis, esophago

Long-term drug treatment is not valid; due to drug dependence affects quality of life or adverse drug reaction occurs; cannot withstand lifelong users; law of medication but reflux-related complications (esophagitis, esophageal stenosis, esophageal Barrett,s) and accompanied by HH.

Long-term medicine treatment invalid; Because the medicine dependence influence quality of life or appears the medicine not good reactor; Is unable to endure the lifelong people treated with medication; But the rule takes medicine appears the regurgitation related complication (esophagitis, esophago