求翻译：与A组相比，B、C、D组各项指标均有明显改变（P＜0.05）,而C组与B组和D组相比，HO-1表达量、HO-1 活性明显升高（P＜0.05）；血清Cr 、IL-6、MCP-1、MDA水平则明显降低（P＜0.05）；肾损伤程度明显减轻。结论 CMN可诱导HO-1表达，并通过HO-1的抗炎症和抗氧化应激机制防止CIN，保护肾脏功能。是什么意思？

Compared with group A, B, C, D group had significant changes in the indicators (P <0.05), while group B and group C and D group, HO-1 expression, HO-1 activity was significantly higher (P <0.05); serum Cr, IL-6, MCP-1, MDA levels were significantly lower (P <0.05); kidney damage is reduced

Compared with A B C , D group, all indicators (P has obviously changed C group <0.05 ) and with B HO group and D group - 1 compared to express volume 1 , HO - reactive pronounced increase (P Cr , <0.05 ); serum MCP IL -6, -1, MDA P performance was markedly reduced ( <0.05 ); renal injury is

Compares with A group, B, C, D group of each target have change obviously (P<0.05), but C group compares with B group and D group, the HO-1 expression quantity, the HO-1 activeness elevate obviously (P<0.05); Blood serum Cr, IL-6, MCP-1, MDA level then reduces obviously (P<0.05); The kidney

Compared with the group a, b, c, d, group indicators are significantly changed (P<0.05), while group c compared with Group b and d, activity significantly elevated expression of HO-1, HO-1 (P<0.05), Cr, IL-6, MCP-1 and MDA in serum levels are significantly lower (P<0.05); kidney damage sign

Compared with the group a, b, c, d, group indicators are significantly changed (P<0.05), while group c compared with Group b and d, activity significantly elevated expression of HO-1, HO-1 (P<0.05), Cr, IL-6, MCP-1 and MDA in serum levels are significantly lower (P<0.05); kidney damage sign