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关注:1
2013-05-23 12:21
求翻译:For instance, MLL2-depleted ES cells showed no obvious defect in their self-renewal capabilities, although they had an enhanced rate of apoptosis and growth impairment in the undifferentiated state and during the first days of differentiation 25,155. However, the depletion of essential and non-redundant MLL-comple是什么意思? 待解决
悬赏分:1
- 离问题结束还有
For instance, MLL2-depleted ES cells showed no obvious defect in their self-renewal capabilities, although they had an enhanced rate of apoptosis and growth impairment in the undifferentiated state and during the first days of differentiation 25,155. However, the depletion of essential and non-redundant MLL-comple
问题补充: |
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2013-05-23 12:21:38
例如, MLL2贫ES细胞显示出在其自我更新的能力没有明显的缺陷,尽管它们在未分化的状态,并在分化25155的第一天有细胞凋亡和生长受损的增强率。
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2013-05-23 12:23:18
正在翻译,请等待...
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2013-05-23 12:24:58
例如, MLL2被耗尽的ES细胞在他们的自新能力没有显示明显的瑕疵,虽然他们有apoptosis和成长损伤的改进的率在无差别的状态和在第一天分化期间25,155。 然而,根本和非冗余的MLL复杂组分的取尽是非常情报对此8,156。 特别是, WDR5在染色体显示为ES细胞自新8需要通过物理互动和强colocalizing与OCT4,包括在自新基因的促进者,维护高水平H3K4me3和transcriptional活化作用7是必要的。
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2013-05-23 12:26:38
例如,MLL2 耗尽的胚胎干细胞显示没有明显的缺陷在其自我更新的能力,虽然他们有细胞凋亡和生长障碍增强的率在未分化状态和分化 25,155 第一天。然而,基本和非冗余 MLL 复杂组件的枯竭一直在 8,156 这方面的内容非常丰富。尤其是,WDR5 被证明需由物理相互作用和强烈 colocalizing 与 OCT4 基因组,包括自我更新基因的启动子中 ES 细胞的自我更新 8 哪里有必要维持高水平的 H3K4me3 和转录激活 7。
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2013-05-23 12:28:18
正在翻译,请等待...
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