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关注:1
2013-05-23 12:21
求翻译:Posaconazole is primarily metabolized via UDP glucuronidation and is a substrate of p-glycoprotein efflux. Therefore, inhibitors or inducers of these clearance pathways may affect posaconazole plasma concentrations. Coadministration of drugs that can decrease the plasma concentrations of posaconazole should generally b是什么意思?![]() ![]() Posaconazole is primarily metabolized via UDP glucuronidation and is a substrate of p-glycoprotein efflux. Therefore, inhibitors or inducers of these clearance pathways may affect posaconazole plasma concentrations. Coadministration of drugs that can decrease the plasma concentrations of posaconazole should generally b
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2013-05-23 12:21:38
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2013-05-23 12:23:18
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2013-05-23 12:24:58
Posaconazole通过UDP glucuronidation主要代谢并且是p糖蛋白废气流基体。 所以,这些清除路抗化剂或引者也许影响posaconazole血浆集中。 可能减少posaconazole的血浆集中药物的Coadministration应该一般避免,除非好处胜过风险。 如果这样药物是必要的,患者应该为突破真菌感染严密被监测。
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2013-05-23 12:26:38
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2013-05-23 12:28:18
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