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关注：1
2013-05-23 12:21
求翻译：Nucleoside analogues are extremely valuable compounds in medicinal chemistry. Modification of the furanose moiety and its impact on the conformation and biological activity of nucleosides has been studied extensively. Due to their more challenging accessibility, ring-expanded derivatives have been considerably less exp是什么意思？ 待解决
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Nucleoside analogues are extremely valuable compounds in medicinal chemistry. Modification of the furanose moiety and its impact on the conformation and biological activity of nucleosides has been studied extensively. Due to their more challenging accessibility, ring-expanded derivatives have been considerably less exp
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2013-05-23 12:21:38
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2013-05-23 12:23:18
Nucleoside类似物是极有价值的化合物在药物化学。 修改furanose半身及其影响的构造和生物活动的含有已被广泛研究。 由于其更具挑战性、可访问性环扩大衍生工具已大大少探讨。 -Hexose和hexitol的含有最研究这一类的,第一次说明了,Eschenmoser Herdewijn组、分别。
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2013-05-23 12:24:58
核苷类似物是极端可贵的化合物在医药化学。 Modification of the furanose moiety and its impact on the conformation and biological activity of nucleosides has been studied extensively. Due to their more challenging accessibility, ring-expanded derivatives have been considerably less explored. Hexose- and hexitol-based nucl
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2013-05-23 12:26:38
核苷类似物是极有价值的化合物在药物化学。广泛地研究了改性呋喃基团及及其对核苷的构象及生物活性的影响。由于他们更具挑战性的辅助功能，扩大环衍生物大大少探讨了。基于己糖和菇类的核苷是最中此类研究，并首先分别介绍了它的全和 Herdewijn 的群体。在菇类系列 (1) 中，灵活的呋喃环取代用更严格的六五元糖戒指，和碱基的位置从基碳移到 3 ′-位置 (图 1)。来自菇类核苷核酸已被证明对基因沉默、 生物和合成生物学的应用程序有用。
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2013-05-23 12:28:18
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