|
关注:1
2013-05-23 12:21
求翻译:Lenalidomide (Len) directly binds to an E3 ubiquitin ligase complex co-receptor protein named cereblon, resulting in sequestering of the ubiquitination complex and alternating the expression of the associated substrate(s) to be identified. Len then causes downregulation of IRF4 and leads to inhibition of BCR dependent 是什么意思? 待解决
悬赏分:1
- 离问题结束还有
Lenalidomide (Len) directly binds to an E3 ubiquitin ligase complex co-receptor protein named cereblon, resulting in sequestering of the ubiquitination complex and alternating the expression of the associated substrate(s) to be identified. Len then causes downregulation of IRF4 and leads to inhibition of BCR dependent
问题补充: |
|
2013-05-23 12:21:38
null
|
|
2013-05-23 12:23:18
正在翻译,请等待...
|
|
2013-05-23 12:24:58
正在翻译,请等待...
|
|
2013-05-23 12:26:38
来那度胺 (Len) 直接绑定到名为 cereblon,E3 泛素连接酶共同的受体蛋白导致封存的复杂的泛素化和交替的表达式相关联的 substrate(s) 待定。Len 然后导致 IRF4 下调导致的 BCR 依赖 NF jB 信号或其他可能的途径,最终导致损害的生长和存活的 ABC DLBCL 细胞的抑制作用
|
|
2013-05-23 12:28:18
正在翻译,请等待...
|
湖北省互联网违法和不良信息举报平台 | 网上有害信息举报专区 | 电信诈骗举报专区 | 涉历史虚无主义有害信息举报专区 | 涉企侵权举报专区