求翻译：（1）体外高糖刺激小管上皮细胞激活NLRP3炎症小体信号通路，使NLRP3表达增加，ASC蛋白表达增加，诱导细胞炎性因子IL-1β增加，48h时表达最为明显。是什么意思？

(1) in vitro high-glucose-stimulated activation of NLRP3 tubular epithelial cells in inflammatory signaling pathways body, so that increased expression of NLRP3, ASC protein expression, induced increase in inflammatory cytokines IL-1β, 48h, expressed the most obvious.

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(1) in vitro high sugar stimulation acorn tube epithelial cell activates the NLRP3 inflammation small body signal passage, causes NLRP3 to express increases, the ASC protein expression increases, induction cell inflammatory factor IL-1β increase, when 48h expresses obviously.

(1) in vitro stimulated by high glucose NLRP3 inflammation of small tubular epithelial cells activated signal transduction, NLRP3 increased expression, ASC increased protein expression, induction of inflammatory cytokine IL-1 β increase, 48h expressed most distinctly.

(1)The tall sugar stimulates the leather cells on the low tube to activate NLRP3 inflammation little body signal thorough fare outside the body, make NLRP3 express that increase, ASC albumen expresses that increases, induces cell inflammation factor IL-1β to increase, 48h expresses hour it is the mo