求翻译：Clinical trials with celecoxib have demonstrated that it is effective in the treatment of chronic pain in patients with rheumatoid arthritis and osteoarthritis In patients with moderate to severe postsurgical dental pain, celecoxib dosed at 100 to 400 mg has been shown to provide clinically significant pain relief throughout an 8-hour postdose assessment period. The studies described in this paper assessed the efficacy and tolerability是什么意思？

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