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关注：1 2013-05-23 12:21

求翻译：A series of pyrimidine based inhibitors of PDE7 are discussed. The synthesis, structure-activity relationships (SAR) and selectivity against several other PDE family members as well as activity in T cells are presented. These compounds were found to have effects on T cell proliferation, however it is not clear whether the mechanism is related to PDE7 inhibition是什么意思？

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A series of pyrimidine based inhibitors of PDE7 are discussed. The synthesis, structure-activity relationships (SAR) and selectivity against several other PDE family members as well as activity in T cells are presented. These compounds were found to have effects on T cell proliferation, however it is not clear whether the mechanism is related to PDE7 inhibition
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2013-05-23 12:26:38
讨论了一系列基于嘧啶抑制剂 PDE7。提出了合成、 结构-活性关系 （香港特别行政区） 和几个其他偏微分方程家庭成员对选择性以及 T 细胞活性。这些化合物发现有对 T 细胞增殖，但尚不清楚是否 PDE7 抑制相关机制
 
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