求翻译：1. Most drugs are well absorbed from the gastrointestinal tract. The rate of absorption depends on the non-ionized fraction of drug in solution. Lipid soluble drugs reach all compartments, and may accumulate in fat. The amount of a drug that is bound to protein depends on three factors: the free drug concentration, its affinity of the binding sites and the protein concentration. Most drugs are metabolized before being eliminated from the body. There are three basic process that account for the renal excretion of drugs and drug metabolites: glomerular filtration, active tubular secretion or reabsorption and passive diffusion across tubular epithelium.是什么意思？

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