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  • 匿名
关注:1 2013-05-23 12:21

求翻译:PDE4 inhibition by cilomilast attenuates bleomycin-induced pulmonary fibrosis in mice. Primarily, cilomilast exerts its beneficial effects via reduction of inflammatory response, although it does not significantly affect neutrophils release. Cilomilast treatment also moderately affects tissue remodeling at late fibrosis stage. This seems to be the consequence of its anti-inflammatory action, although direct effect on tissue remodeling via inflammation-independent mechanism is highly possible.是什么意思?

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PDE4 inhibition by cilomilast attenuates bleomycin-induced pulmonary fibrosis in mice. Primarily, cilomilast exerts its beneficial effects via reduction of inflammatory response, although it does not significantly affect neutrophils release. Cilomilast treatment also moderately affects tissue remodeling at late fibrosis stage. This seems to be the consequence of its anti-inflammatory action, although direct effect on tissue remodeling via inflammation-independent mechanism is highly possible.
问题补充:

  • 匿名
2013-05-23 12:26:38
Cilomilast PDE4 抑制抑制小鼠博莱霉素致肺纤维化。主要是 cilomilast 施加的炎症反应,减少通过有益的影响,虽然它并不会显著影响中性粒细胞释放。Cilomilast 治疗也温和影响组织重构晚纤维化阶段。这似乎是后果及其抗炎行动,虽然对组织重构通过独立的炎症反应机制的直接影响是很有可能。
 
 
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