求翻译：ICU医院感染与患者年龄、病情危重程度及抗生素的滥用、创伤性操作等因素相关。应采取加强ICU病室管理、严格无菌操作、合理应用抗生素等措施控制和降低医院感染的发生。是什么意思？

Patients with nosocomial infection in ICU and age, a critical condition and antibiotics related to factors such as abuse, traumatic operation. Should be taken to strengthen management of ICU Ward, strict aseptic operation and reasonable application of antibiotics and other measures to control and reduce the incidence of nosocomial infection.