求翻译：3.2　由高剂量测试向低剂量测试发展　以基因组表达谱、蛋白质组表达谱、代谢组谱、生物标志物等敏感、特异的毒性指标体系将替代或部分替代以死亡、组织病理学为主的传统毒性指标体系。从而阐明和评价更接近实际条件下暴露剂量对人体和其他生物的毒性效应,解决从高剂量向低剂量外推时不肯定性带来的误差。是什么意思？

3.2 to the development of low-dose test by high-dose test to genome expression profiling, protein expression, metabolism group spectrum, biomarkers of toxicity to sensitive, specific indicators, such as system will replace or substitute for histopathology to death, mainly traditional toxicity index system. So as to clarify the closer to the actual conditions and evaluation of exposure dose to humans and other organisms toxicity, resolve uncertainty when high doses of to low-dose extrapolation of the error.