求翻译：目前已有人提出在合理药物设计过程中,提前对药物的ADME 性质和毒性进行评估,避免在后面的开发过程中才发现问题,以减少药物开发成本是什么意思？

Has been raised in the process of rational drug design, drug adme in advance of the nature and toxicity assessment, to avoid later problems discovered during development, in order to reduce drug development costs

Currently has been made in rational drug design process, to advance the ADME nature and toxic substances, and to avoid being left behind in assessing problems were identified during the development process, in order to reduce drug development costs

At present some people proposed in the reasonable medicine design process, ahead of time carries on the appraisal to the medicine ADME nature and the toxicity, avoids only then finding the problem in the behind performance history, reduces the medicine development cost

At present has been made in rational drug design process, the assessment of ADME properties and toxicity of drugs in advance to avoid later problems discovered during the development, in order to reduce drug development costs