求翻译：细胞生长过程中不断消耗O2并产生CO2，pH也随之下降，仅这一变化就会威胁到细胞的存活，严重影响其增殖和分化[ ]。是什么意思？

Draining the O2 during cell growth, and decline the CO2,pH, only the change would have threatened the survival of cells, seriously affecting their proliferation and differentiation of [].