求翻译：当生物反应器长时间工作，新鲜培养液中主要营养成分不足或代谢产物较多时，更换新的一次性无菌包装的营养液。是什么意思？

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When bio-reactor work long hours, mainly in fresh produce liquid nutrient deficiencies or more metabolic, replacement of the one-time aseptic packaging of nutritional fluid.

When the biological reactor long-firing operation, in the fresh nutrient fluid the main nutrition ingredient insufficiency or the metabolite are many, replaces the new disposable asepsis packing the nourishing cream.

When a biological reactor to work long hours, lack of main nutritional components in fresh culture medium or metabolites during periods, replacement of disposable aseptic nutrient solution.